The USC Creative Media & Behavioral Health Center (CM&BHC) is an organized research unit between the School of Cinematic Arts and the Keck School of Medicine.

The Game Innovation Lab is the premier center for experimental game design research at USC. Founded in 2004, the lab is directed by Professor Tracy Fullerton. The mission of the lab is to pursue experimental design of games in cultural realms including art, science, politics and learning.

MxR at the University of Southern California explores techniques and technologies to improve the fluency of human-computer interactions and create visceral synthetic experiences.

The Mobile and Environmental Media Lab is currently exploring location-specific mobile storytelling. This research investigates the idea of ambient storytelling and how the built environment can act as a storytelling entity that engages and interacts with people in specific spaces.